Paul N Newton Selected Research

Mefloquine (Lariam)

1/2020	Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised clinical trial.
12/2010	A phase III, randomized, non-inferiority trial to assess the efficacy and safety of dihydroartemisinin-piperaquine in comparison with artesunate-mefloquine in patients with uncomplicated Plasmodium falciparum malaria in southern Laos.
7/2010	An open-label, randomised study of dihydroartemisinin-piperaquine versus artesunate-mefloquine for falciparum malaria in Asia.
10/2004	Randomized comparison of chloroquine plus sulfadoxine-pyrimethamine versus artesunate plus mefloquine versus artemether-lumefantrine in the treatment of uncomplicated falciparum malaria in the Lao People's Democratic Republic.

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Paul N Newton Research Topics

Disease

44	Malaria 01/2023 - 01/2003
36	Infections 01/2023 - 10/2005
32	Falciparum Malaria (Plasmodium falciparum Malaria) 12/2020 - 04/2002
18	Scrub Typhus (Typhus, Scrub) 12/2023 - 02/2008
16	Dengue (Dengue Fever) 11/2022 - 04/2006
14	Fever (Fevers) 01/2023 - 09/2003
8	Endemic Flea-Borne Typhus (Typhus, Endemic Flea Borne) 01/2020 - 05/2009
7	Melioidosis 02/2024 - 03/2003
7	Central Nervous System Infections (Central Nervous System Infection) 12/2019 - 08/2011
5	Typhoid Fever (Typhoid) 01/2020 - 06/2005
4	Leptospirosis 02/2024 - 07/2010
4	Japanese Encephalitis 01/2023 - 12/2015
4	Body Weight (Weight, Body) 07/2014 - 04/2005
3	Communicable Diseases (Infectious Diseases) 02/2024 - 02/2014
3	Epidemic Louse-Borne Typhus (Typhus) 12/2023 - 02/2008
3	Coma (Comas) 01/2022 - 07/2003
3	Bacterial Infections (Bacterial Infection) 01/2022 - 11/2015
3	Beriberi 12/2020 - 02/2011
3	Bacteremia 01/2020 - 01/2013
3	Sepsis (Septicemia) 01/2020 - 09/2003
3	Jaundice (Icterus) 01/2015 - 08/2009
2	COVID-19 11/2023 - 01/2020
2	Pneumococcal Infections 01/2022 - 12/2019
2	Pneumonia (Pneumonitis) 01/2022 - 09/2020
2	Abscess 01/2020 - 08/2017
2	Vivax Malaria 01/2020 - 01/2019
2	Acute Febrile Encephalopathy 03/2019 - 07/2012
2	Meningitis 12/2017 - 07/2012
2	Inflammation (Inflammations) 01/2016 - 01/2015
2	Reinfection 01/2016 - 10/2004
2	Virus Diseases (Viral Diseases) 01/2016 - 11/2015
2	Acute malaria 01/2015 - 12/2003
2	Cryptococcal Meningitis 12/2012 - 09/2002
2	Hepatitis 07/2010 - 08/2009
2	Heart Failure 11/2007 - 09/2003
1	Seizures (Absence Seizure) 12/2022
1	Meningoencephalitis 10/2022
1	Autoimmune Diseases of the Nervous System 10/2022
1	Tuberculosis (Tuberculoses) 01/2022
1	Hypoxia (Hypoxemia) 09/2020
1	Vomiting 01/2020
1	Hemolysis 01/2019
1	Glucosephosphate Dehydrogenase Deficiency 01/2019

Drug/Important Bio-Agent (IBA)

23	Immunoglobulin M (IgM)IBA 02/2024 - 04/2006
23	Antimalarials (Antimalarial Agents)IBA 11/2020 - 04/2002
22	Anti-Bacterial Agents (Antibiotics)IBA 02/2024 - 06/2005
17	artemisinin (artemisinine)IBA 01/2022 - 02/2008
16	ArtesunateIBA 03/2015 - 04/2002
14	AntigensIBA 02/2024 - 03/2004
13	Immunoglobulin G (IgG)IBA 12/2023 - 04/2006
13	AntibodiesIBA 01/2023 - 04/2006
11	EnzymesIBA 12/2023 - 08/2005
10	ImmunosorbentsIBA 12/2023 - 08/2005
8	artenimol (dihydroartemisinin)IBA 01/2020 - 04/2002
8	Doxycycline (Periostat)FDA LinkGeneric 01/2020 - 04/2005
6	VaccinesIBA 11/2023 - 06/2013
6	Thiamine (Aneurin)FDA Link 12/2020 - 09/2003
6	piperaquineIBA 01/2020 - 07/2010
6	Biomarkers (Surrogate Marker)IBA 11/2019 - 02/2011
6	Chloroquine (Aralen)FDA LinkGeneric 06/2012 - 05/2003
5	Conjugate VaccinesIBA 01/2022 - 01/2020
5	Lumefantrine Drug Combination Artemether (Coartem)FDA Link 01/2020 - 10/2004
5	RNA (Ribonucleic Acid)IBA 12/2019 - 01/2016
5	Quinine (Quinson)FDA Link 10/2014 - 07/2003
5	TabletsIBA 07/2014 - 01/2003
4	Proteins (Proteins, Gene)FDA Link 01/2023 - 09/2012
4	TransketolaseIBA 12/2020 - 03/2007
4	Primaquine FDA Link 01/2020 - 11/2018
4	Mefloquine (Lariam)FDA LinkGeneric 01/2020 - 10/2004
3	FluoroquinolonesIBA 01/2020 - 04/2010
3	Chloramphenicol (Chloromycetin)FDA Link 01/2019 - 06/2005
3	Artemether FDA Link 01/2018 - 12/2003
3	pyrimethamine drug combination fanasil (Fansidar)FDA Link 10/2004 - 05/2003
2	Oxygen (Dioxygen)IBA 01/2022 - 09/2020
2	Viral RNAIBA 03/2019 - 01/2016
2	Azithromycin (Zithromax)FDA LinkGeneric 01/2019 - 01/2018
2	SoilIBA 01/2018 - 01/2011
2	C-Reactive ProteinIBA 01/2016 - 11/2015
2	ArtemisininsIBA 11/2013 - 08/2011
2	Lactic Acid (Lactate)FDA LinkGeneric 02/2009 - 07/2003
2	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 11/2007 - 04/2006
2	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 10/2005 - 10/2005
1	Polysaccharides (Glycans)IBA 02/2024
1	ProteomeIBA 01/2023
1	Malaria VaccinesIBA 01/2023
1	Counterfeit DrugsIBA 12/2022
1	Environmental DNAIBA 12/2022
1	Complement System Proteins (Complement)IBA 12/2022
1	AutoantibodiesIBA 10/2022
1	Diphosphates (Pyrophosphates)IBA 12/2020
1	1- eicosanoyl- 3''- N- (trifluoroacetyl)kanamycin (ETKA)IBA 12/2020
1	8-aminoquinolineIBA 01/2020
1	Amodiaquine (Camoquin)FDA Link 01/2020
1	beta-Lactamases (beta-Lactamase)IBA 01/2020
1	Peptides (Polypeptides)IBA 11/2019
1	mesoglycanIBA 11/2019
1	tafenoquineIBA 01/2019

Therapy/Procedure

19	Therapeutics 01/2020 - 10/2003
6	Mass Drug Administration 08/2021 - 01/2018
2	Insecticide-Treated Bednets 11/2018 - 02/2013